TOPIC: Heard of PMMA (Medical Grade) OR Dr Casavantes? [PART 2]

@HC

I think you may be right by thinking that the PMMA "MAY" effect all that stuff that you are doing at once. I'd suggest a staged plan. Finish the medical stuff first, then give it a few month to stabilize then go for PMMA.

@Dd71: Some colour on effects from silicone migration follows below. If scientific evidence is any guide (it bloody is), whatever the specific effects of low quality PMMA migration (possibly unknown at present) are, we really want to stay clear.

As early as 1956, Dow Chemical researchers knew that liquid silicone, when injected into the body, migrates to all the major organs, including the spleen, , lung, and brain. (PSC Record No. 0006.)
Studies by both Dow Corning and Dow Chemical in 1970 confirmed that silicone, after injection, migrates to the bone marrow of animals and changes brain weight. They also showed that silicone particles migrate from a human finger joint into the lymph nodes. (PSC Record No. 0018, 7038.)
Researchers at Baylor College of Medicine in Texas found that silicone is widely distributed throughout the body of mice after a single injection, migrating to ten different organs from the brain to the uterus and persisting in these organs over time. (American Journal of Pathology 152:3 [March 1998], 645-649.)
Researchers at the Medical College of Wisconsin in Milwaukee found that following silicone implant rupture, silicone gel migrated into the arm of a woman, where it produced nerve pain, dysfunction, and fibrosis. (Plastic Reconstructive Surgery 89:5 [May 1992], 949-952.)
Physicians at Massachusetts General Hospital in Charlestown, using magnetic resonance imaging, found that a significant amount of free siliconehad migrated from an implant (not noticeably ruptured) into the liver and spleen of a woman. (Magnetic Resonance Medicine 36:3 [September 1996], 498-501. Researchers also found that silicone in the liver could be detected in the first three to four years after a woman received her implant. (Magnetic Resonance Medicine 33:1[January 1995], 8-17.)
Of 39 women with silicone implants, 27 (69%) showed signs of silicone in their livers, and of the 20 whose implants had ruptured, silicone was detected in the livers of 17 (85%). In other words, whether the implants rupture or not, silicone leaks and migrates to the liver. (Radiology 201 [1996], 777-783; PSC Record No. 0050.)
In 1989, studies by Dow Corning showed that silicone, given orally to rats, increased liver size and weight by up to 45% and suggested the enlargement might be interpreted as a carcinogenic response. (PSC Record No. 0482.)

@smartman
do you think the Professor would be willing to join the discussion community, or at least join this thread?

at the risk of sounding naive, what would be potential complications due to migration with PMMA?

@SO

As mentioned in my posts, in the legend you read that EM picture of Artefill has been zoomed 400x. Length unit of the picture is reported to be 100 microns. In contrast, EM picture of Newplastic has been zoomed 250x and the length unit is 200 microns. I have also noted that in the legend the lengths of the two length units is different whilst the dimensions of the two pictures are the same.

And my point just was: why would you use different zooms and length units in pictures if you want to optically compare shapes??? I cannot see the scientific logic behind! The only explanation I can come up with is that the zooming choice simply reflects the bias of the author of the article (other possible explanations from forum members are welcome).
I paste below the disclosures at the end of the Cohen's article:

Dr. Steven R. Cohen is on the Medical Advisory Board of Suneva Medical, Inc., the company that manufactures and distributes ArteFill. He has received stock options and periodicreimbursement for travel, lodging, and consulting. He is also aninvestigator in the FDA postapproval safety study for ArteFill.

As I have stated in the past, please take anything Lemperle states with a grain of salt.
With that said, the studies posted here recently and others I posted in the past show the potential for PMMA, more specifically New Plastic, to migrate. If a substance can be phagocytized it can migrate.

If you don't think New Plastic was shown to be phagocytized please read ALL the posted studies on this forum and on forum 1.0.

supa wrote: Guys, I cant see my attachments in my past two posts anymore (the EM pictures). Have they been removed?

I can still see them. Be sure you are logged in, because that is the only way to see uploaded photos.
If you are logged in and still cannot see them, please let me know.

Isn't the big difference here that the PMMA binds with natural collagen to basically integrate with your own tissue in a way that injected silicone does not, which prevents migration?

Electronic microscopic images of Artefill attached below (S. Cohen, Aesthetic Surgery Journal 2010 30:438).

I am also considering an adjunct to the DHT gel combined with DMSO: it is the gel form of TriMax which itself is an injectible combination of:
AlprostadilprostaglandinPapaverinevasodilatorPhentolaminealpha blocker
In gel form TriMax-Gel could be applied at the same time as Andractim DHT cream along with DMOS and this mixture would be especially capable of penetrating the shaft and glans throughout all of their structures. This might have an added benefit of placing the ingredients in the central soft tissue structure leading up to the glans, (which presumably wouldn't be reached by a shaft base injection into one of the two lateral veinous structures) ensuring a more coherent hormonal response throughout all bodies of this organ. This topical application of TriMax-Gel (with or without DHT) could presumably be done instead of or in addition to a Erectile Disfunction daily injection of TriMax injectible or another ED injection at the base... FWIW
HC

cantwaitforpma wrote: Hello all. Just wanted to introduce myself. Because i'm paranoid about posting my name i hope yall don't mind just knowing me as M. Thank you all who have taken the plunge and gotten the PMMA procedure done. I've been reading or "lurking" at the old forum and can't wait till i can contribute and add to the wealth of information and experience knowledge yall have made available. I'm ready to shed my lack of self confidence(all psychological) and start being a more confident person for both me and my wife. Thank you so much for again for your contributions.

Welcome to the forum! Judging from your username, do you have an appointment schedule or plan to schedule one? Or are you still in the research phase?

Indeed, all available literature I have come across, except for the two 2010 Aesthetic Surgery Journal papers which we have discussed in the last pages of this thread in the old forum, seem to rule out the possibility of migration.

But, here, d71 just asked the question: what happens if PMMA's beads migrate.

Does it happen?

Let us be clear that what has surprised us is that the sheer possibility of migration of PMMA particles in Newplastic has been raised in the two quoted papers. Is it true? Only a couple of articles make this claim; I felt initially a bit uneasy however since the journal looks authoritative, the articles are recent and they bring clinical evidence.

On the other hand, as correctly repeated here, PMMA long history has got a completely different track record from SILICONE.

For what is worth, my gut feeling is that migration concerns for Newplastic are overdone, even if it clearly is inferior in quality to Artefill. Dr Casavantes has got an international reputation in his field which he has gained over many years: he must trust this product and that we need to keep in mind when we think of risk scenarios.

Electronic microscopic images of Newplastic attached below (S. Cohen, Aesthetic Surgery Journal 2010 30:438).

Hi Guys,
I'm calling forth your advice regarding the compatibility of PMMA injections with ulterior NATURAL growth enhancement. I am starting to undertake intensive hormonal treatments associated with directly injected vascular enhancers. This means that once I get my first session of PMMA and its associated collagen buildup my penis might still grow a good bit if the testimony seen below is valid.
phalloboards.websitetoolbox.com/post/sho...9224459&postcount=11
I am starting to take Chorionic Gonodotropin (better known as Pregnyl) at 3000 IU per week injected under the pelvic skin. I plan to also take a strong Erectile Dysfunction injection daily directly into the penis - ouch! Add to that DHT with enhanced penetration using DMSO as a carrier and there is a small chance of actually experiencing noteworthy penis growth by chemical means. Wouldn't the collagen strands generated by PMMA, with their harder buidup, tend to resist growth pressure not so much longitudinally but mostly of girth? The last thing I want is for PMMA induced collagen layers to PREVENT harmonious penis englargement and reduce my girth potential ? ! ?
HC