TOPIC: Heard of PMMA (Medical Grade) OR Dr Casavantes? [PART 2]

hi brittani, I'm not sure if you are aware of this, but you've just joined a site dedicated to penis enlargement!

But I'm sure if you were to post some photos we could advise you very wisely regarding your butt.

Sorry fellas, the thread is unlocked now.

This was his answer about the possibility of infection of the PMMA have not heard of an infected PMMA implant ! It contains millions of macrophages , which would every bacteria at once ! However, if an abscess is close by, one has to open and drain the abscess as usual - without antibiotics ! The near PMMA will help the healing of the abscess hole since it is well vascularized and bleeds when you cut through. It has not to be removed but heals like fresh scar tissue.

@SO
No problem I will ask him , but I know he is very busy guy travelling a lot (giving lectures, treating some patients e.g. in China and Cambodia and other countries) , now he is busy with his research project about the treatment of reflux esophagitis with large microspheres PMMA injection . By the way he is >75 y.o.

@smartman ' do you know if Dr. Lemperle has any official affiliation with Suneva Medical Inc the new owning entity of Artefill? Does he have any affiliation with NewPlastic?The reason I am asking is that it seems very clear from Dr. Cohen's commentary and also from a consultation I had today with a local plastic surgeon, who does a lot of Artefill procedures, is that there is clear emphasis on the point that Artefill is very different than NewPlastic. The point that Arteplast was a 'flawed product with significant issues' was raised over and over in my consultation, as was the point that NewPlastic and Precise are very similar to the older generation Arteplast product.This particular doctor was very high on Artefill and claimed to have done several thousand injections and several hundred Artefill injections!

@Dd71: Some colour on effects from silicone migration follows below. If scientific evidence is any guide (it bloody is), whatever the specific effects of low quality PMMA migration (possibly unknown at present) are, we really want to stay clear.

As early as 1956, Dow Chemical researchers knew that liquid silicone, when injected into the body, migrates to all the major organs, including the spleen, , lung, and brain. (PSC Record No. 0006.)
Studies by both Dow Corning and Dow Chemical in 1970 confirmed that silicone, after injection, migrates to the bone marrow of animals and changes brain weight. They also showed that silicone particles migrate from a human finger joint into the lymph nodes. (PSC Record No. 0018, 7038.)
Researchers at Baylor College of Medicine in Texas found that silicone is widely distributed throughout the body of mice after a single injection, migrating to ten different organs from the brain to the uterus and persisting in these organs over time. (American Journal of Pathology 152:3 [March 1998], 645-649.)
Researchers at the Medical College of Wisconsin in Milwaukee found that following silicone implant rupture, silicone gel migrated into the arm of a woman, where it produced nerve pain, dysfunction, and fibrosis. (Plastic Reconstructive Surgery 89:5 [May 1992], 949-952.)
Physicians at Massachusetts General Hospital in Charlestown, using magnetic resonance imaging, found that a significant amount of free siliconehad migrated from an implant (not noticeably ruptured) into the liver and spleen of a woman. (Magnetic Resonance Medicine 36:3 [September 1996], 498-501. Researchers also found that silicone in the liver could be detected in the first three to four years after a woman received her implant. (Magnetic Resonance Medicine 33:1[January 1995], 8-17.)
Of 39 women with silicone implants, 27 (69%) showed signs of silicone in their livers, and of the 20 whose implants had ruptured, silicone was detected in the livers of 17 (85%). In other words, whether the implants rupture or not, silicone leaks and migrates to the liver. (Radiology 201 [1996], 777-783; PSC Record No. 0050.)
In 1989, studies by Dow Corning showed that silicone, given orally to rats, increased liver size and weight by up to 45% and suggested the enlargement might be interpreted as a carcinogenic response. (PSC Record No. 0482.)

@smartman
do you think the Professor would be willing to join the discussion community, or at least join this thread?

at the risk of sounding naive, what would be potential complications due to migration with PMMA?

As I have stated in the past, please take anything Lemperle states with a grain of salt.
With that said, the studies posted here recently and others I posted in the past show the potential for PMMA, more specifically New Plastic, to migrate. If a substance can be phagocytized it can migrate.

If you don't think New Plastic was shown to be phagocytized please read ALL the posted studies on this forum and on forum 1.0.

Isn't the big difference here that the PMMA binds with natural collagen to basically integrate with your own tissue in a way that injected silicone does not, which prevents migration?

Electronic microscopic images of Artefill attached below (S. Cohen, Aesthetic Surgery Journal 2010 30:438).

cantwaitforpma wrote: Hello all. Just wanted to introduce myself. Because i'm paranoid about posting my name i hope yall don't mind just knowing me as M. Thank you all who have taken the plunge and gotten the PMMA procedure done. I've been reading or "lurking" at the old forum and can't wait till i can contribute and add to the wealth of information and experience knowledge yall have made available. I'm ready to shed my lack of self confidence(all psychological) and start being a more confident person for both me and my wife. Thank you so much for again for your contributions.

Welcome to the forum! Judging from your username, do you have an appointment schedule or plan to schedule one? Or are you still in the research phase?

Indeed, all available literature I have come across, except for the two 2010 Aesthetic Surgery Journal papers which we have discussed in the last pages of this thread in the old forum, seem to rule out the possibility of migration.

But, here, d71 just asked the question: what happens if PMMA's beads migrate.

Does it happen?

Let us be clear that what has surprised us is that the sheer possibility of migration of PMMA particles in Newplastic has been raised in the two quoted papers. Is it true? Only a couple of articles make this claim; I felt initially a bit uneasy however since the journal looks authoritative, the articles are recent and they bring clinical evidence.

On the other hand, as correctly repeated here, PMMA long history has got a completely different track record from SILICONE.

For what is worth, my gut feeling is that migration concerns for Newplastic are overdone, even if it clearly is inferior in quality to Artefill. Dr Casavantes has got an international reputation in his field which he has gained over many years: he must trust this product and that we need to keep in mind when we think of risk scenarios.

Electronic microscopic images of Newplastic attached below (S. Cohen, Aesthetic Surgery Journal 2010 30:438).